Download e-book for iPad: Antimicrobial peptides : discovery, design and novel by Guangshun Wang

By Guangshun Wang

ISBN-10: 1845936949

ISBN-13: 9781845936945

Antimicrobial Peptides (AMPs), an organism's integrated security molecules, have attracted wide study consciousness world wide. Harnessing and developing them synthetically has the aptitude to assist triumph over expanding antibiotic resistance in lots of pathogens. as well as overlaying the present advances in AMP examine, this quantity examines new applied sciences comparable to bioinformatics, combinatorial libraries, high-throughput screening, peptidomimetics, biophysics, and structural biology. This quantity additionally describes new equipment and techniques for AMP prediction, layout, and purposes that conquer stumbling blocks in constructing them into healing brokers.

Show description

Read or Download Antimicrobial peptides : discovery, design and novel therapeutic strategies PDF

Similar pharmacy books

New PDF release: Levine's pharmacology: Drug actions and reactions

Thoroughly revised and up to date, this can be the 7th variation of Levine's vintage pharmacology textbook. identified for it really is thorough insurance and clever association, the booklet covers the fundamental rules of pharmacological interactions at the human physique in a manner that's precious for either undergraduate and graduate scholars.

Download e-book for kindle: Stable Isotopes in Pharmaceutical Research by T.R. Browne

Sturdy isotope options provide benefits in protection, sensitivity, specificity, and financial system for plenty of forms of pharmaceutical investigations in comparison to traditional options. however, pharmaceutical researchers are gradual to include strong isotope options. This ebook assembles in a single position entire experiences of the various purposes of good isotopes and the heritage fabric essential to comprehend the applying.

Michael E. Aulton BPharm PhD FAAPS FSP FRPharmS, Kevin's Aulton's Pharmaceutics: The Design and Manufacture of PDF

Pharmaceutics is likely one of the such a lot varied topic parts in all of pharmaceutical technology. in short, it truly is desirous about the clinical and technological points of the layout and manufacture of dosage kinds or medicinal drugs. An figuring out of pharmaceutics is consequently very important for all pharmacists and people pharmaceutical scientists who're concerned with changing a drug or a possible drug right into a medication that may be brought appropriately, successfully and very easily to the sufferer.

Fragment-Based Methods in Drug Discovery by Anthony E. Klon PDF

This quantity covers the options invaluable for a profitable fragment-based drug layout undertaking, starting from defining the matter when it comes to getting ready the protein version, deciding on power binding websites, and the honor of assorted candidate fragments for simulation. the second one half discusses the technical elements that numerous equipment have used to simulate fragment binding to a objective protein through the use of Monte Carlo, molecular dynamics, and docking algorithms.

Additional info for Antimicrobial peptides : discovery, design and novel therapeutic strategies

Example text

De Kruijff, B. and Breukink, E. (2006) An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II. Science 313, 1636– 1637. Hellekant, G. and Danilova, V. (2005) Brazzein a small, sweet protein: discovery and physiological overview. Chemical Senses 30, i88–i89. , MarcianoCabral, F. and Leippe, M. (2002) Pore-forming 19 polypeptides of the pathogenic protozoon Naegleria fowleri. Journal of Biological Chemistry 277, 22353–22360. , Msadek, T. and El Amri, C. (2009) Comparative study of two plasticins: specificity, interfacial behavior, and bactericidal activity.

Salzet, M. and Zasloff, M. (2005) The nervous system and innate immunity: the neuropeptide connection. Nature Immunology 6, 558–564. Bulet, P. and Stocklin, R. (2005) Insect antimicrobial peptides: structures, properties and gene regulation. Protein and Peptide Letters 12, 3–11. F. S. (1998) Enterocins L50A and L50B, two novel bacteriocins from Enterococcus faecium L50, are related to staphylococcal hemolysins. Journal of Bacteriology 180, 1988–1994. , Scalise, G. and Giacometti, A. (2008) Protective effects of the combination of alpha-helical antimicrobial peptides and rifampicin in three rat models of Pseudomonas aeruginosa infection.

2005a) Bacteriocins: developing innate immunity for food. Nature Reviews. Microbiology 3, 777– 788. , Hill, C. P. (2005b) Posttranslational conversion of L-serines to D-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147. Proceedings of the National Academy of Sciences of the USA 102, 18584–18589. , Singh, J. A. (2009) The effect of C-terminal amidation on the efficacy and selectivity of antimicrobial and anticancer peptides. Molecular and Cellular Biochemistry 332, 43–50.

Download PDF sample

Antimicrobial peptides : discovery, design and novel therapeutic strategies by Guangshun Wang


by Richard
4.3

Rated 4.04 of 5 – based on 28 votes
 

Author: admin